关键词: MS222, 气相色谱-质谱, 鱼肉, MS-222, gas chromatohraph-mass spectrum, fish meat

Abstract: A method is established for detecting MS-222 in fish meat by GC-MS. The MS-222 residues is extracted with acetonitrile, ionized in HCL solution, isolated by Waters Oasis MCX SPE column, then detected by GC-Quadrupole Mass Spectrometer. The limits of quantification is 5.0μg?kg-1, linear correlation coefficients of calibration curve is over 0.9996 within the concentration range of 0.0025~1.0μg?mL-1, For the 5.0～100.0μg?kg-1 spiked sample, within-day and day-to-day average recoveries are 78.4~91.2%, RSDs are 3.62~9.49%. From the results of above, this method can be used to detect the low concentration MS222 in fish meat.