欢迎访问《渔业研究》官方网站,今天是 分享到:

›› 2015, Vol. 37 ›› Issue (4): 325-337.

• 综述与其他 • 上一篇    下一篇

海洋来源甾体化合物的生物活性研究进展

吴靖娜,刘智禹,潘南,苏捷,路海霞,蔡水淋   

  1. 福建省水产研究所
  • 收稿日期:2015-03-06 修回日期:2015-05-18 出版日期:2015-08-25 发布日期:2015-08-18
  • 通讯作者: 吴靖娜
  • 基金资助:
    海马甾体化合物的提取及生物活性研究;几种重要海洋珍贵动物活性物质提取工程化技术研发与示范应用项目实施方案

Advanced in bioactive sterols from marine resources

  • Received:2015-03-06 Revised:2015-05-18 Online:2015-08-25 Published:2015-08-18

摘要: 我国海域辽阔,可开发利用的生物资源极其丰富,海洋生物中含有许多结构新颖、活性显著的天然化合物,引起了科研工作者的广泛关注。甾体化合物广泛存在于多种海洋生物体内,它们具有抗肿瘤、抗菌、抗炎和抗病毒等诸多生物活性,现对海洋甾体化合物分离纯化、生物来源、结构特征和生物活性的研究进展加以概述,以期为海洋药物开发提供参考。

关键词: 甾体化合物, 化学结构, 生物活性, sterols, chemical construction, biological activity

Abstract: With marine species abundant, the sea offers enormous resources for structurally diverse natural compounds with various beneficial biological activities. Therefore, increasing knowledge on novel functional ingredients with biological activities from marine organisms has gained much attention. Marine organisms have proven to be a rich source of sterols. Additionally, sterols have been suggested to have anticancer, anti-inflammatory, antibacterial and antiviral activities. This article focuses on purification methods, biogenetic derivation, chemical construction and biological activity of sterols in order to provide reference for marine medicinal development.

中图分类号: