›› 2017, Vol. 39 ›› Issue (2): 147-156.
• 综述与其他 • 上一篇 下一篇
赵景华1,吴兆明1,丁宇宁1,刘文文1,颜泽1,柯冰冰1,沈萍1,胡建恩2
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摘要: 胶原蛋白是动物体内重要的结构蛋白质,因具有生物可降解性、生物相容性、无毒等特性而被广泛应用。本文综述了戊二醛、β-环糊精聚轮烷单醛、丙二酸等交联剂对胶原蛋白进行化学改性的方法研究现状,并介绍了胶原蛋白改性材料在止血、药物运输载体、组织工程支架等方面应用的研究进展。
关键词: 胶原蛋白, 化学改性, 交联剂, collagen, chemical modification, crosslinking agent
Abstract: Collagen is an important structural protein in animal body. It is widely used because oi its biodegradability, biocompatibility and nontoxicity. In this paper, the research progress of the chemical modification of collagen by glutaraldehyde, β- cyclodextrin, polyrotaxane aldehyde, malonic acid and other crosslinking agents was reviewed, and the application of collagen modified materials in hemostatic, drug delivery carrier and tissue engineering scaffold was introduced
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TS254.9
赵景华 吴兆明 丁宇宁 刘文文 颜泽 柯冰冰 沈萍 胡建恩. 胶原蛋白的化学改性方法及其应用的研究进展[J]. , 2017, 39(2): 147-156.
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http://www.hyyysci.com/CN/Y2017/V39/I2/147