Abstract: In the paper,the survival rate of Ruditapes philippinarum,the colony count,the number of Escherichia coli and the number of vibrio in Ruditapes philppinarum were detected,with time changing, when stored at 15℃, 4℃ and -18℃,and the correlations between them were analyzed. The results showed that the survival rate of Ruditapes philippinarum at 4℃ still maintain the 100% saruivel rate of the time of 96 h. The colony count, the number of Escherichia coli and the number of vibrio of Ruditapes philippinarum at -18℃ showed no significant change,with the increase of storage time, and were lower than those at 0 h respectively. In contrast, the colony count and the number of vibrio of Ruditapes philippinarum at 15℃ and 4℃ showed a rising trend at different levels. Meanwhile, the correlation coefficients between them at 15℃ and 4℃ were significant, respectively 0.884, 0.927. However, the number of Escherichia coli showed no significant change at 15℃ and 4℃.