Abstract: The development of marine bio pharmaceutical industry is an inevitable requirement for Shandong Province to implement the strategy of strong marine province,realize the transformation of new and old kinetic energy,and realize the leapfrog development of marine economy.This paper used Gompertz curve to analyze the life cycle stage of Shandong marine bio pharmaceutical industry,and used the diamond model to revise individual factors and summarize the factors affecting the competitiveness of the industry from six aspects:production factors,demand conditions,related and supportive industries,technology and R&D capabilities,government policies and opportunities,and put forward some suggestions for promoting the competitiveness of the industry.