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›› 2014, Vol. 36 ›› Issue (6): 428-435.

• 论文与报告 • 上一篇    下一篇

碱液浸提法制备硫酸软骨素的工艺优化

叶琳弘,刘秋凤,王茵,吴成业   

  1. 福建省水产研究所
  • 收稿日期:2014-08-13 修回日期:2014-09-09 出版日期:2014-12-25 发布日期:2014-12-23
  • 通讯作者: 吴成业
  • 基金资助:
    福建省海洋经济创新发展区域示范项目

Optimization of preparation of chondroitin sulfate by alkali leaching method

Lin-Hong 1, 1,wu chengye   

  • Received:2014-08-13 Revised:2014-09-09 Online:2014-12-25 Published:2014-12-23
  • Contact: wu chengye

摘要: 采用碱液浸提法对鱿鱼软骨中硫酸软骨素的提取ェ艺进行研究。以硫酸软骨素得率为评价指标,通过对影响硫酸软骨素得率的因素进行单因素试验和响应面优化试验确定最佳G工艺参数。結果表明,碱液浸提的最佳ェ艺条件为:料液比1 :8 ( g /m L )、浸提温度5 0℃、浸提时间5. 3 h ,N aO H 浓度3 % 。在此条件下,鱿鱼软骨中硫酸软骨素得率为62 .89 % 。

关键词: 鱿鱼软骨, 碱液浸提, 硫酸软骨素, 响应面优化, squid cartilage, alkali leaching, chondroitin sulfate, response surface optimization

Abstract: The alkali leaching method was used in the extraction process of chondroitin sulfate from squid cartilage.Choosing chondroitin sulfate yield as evaluation index, the best technology parameters were confirmed by single factors and surface response optimization tests. The optimum conditions of leaching technology were obtained as follows : ratio of material to solvent was 1: 8 ( g /m L ) ,leaching temperature was 5 0 C ,leaching time was 5. 3 h ,alkali concentration was 3 % . Under these conditions,the yield of chondroitin sulfate from squid cartilage was 62. 89% .

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