关键词: 鱿鱼；糖蛋白；降血脂；非特异性免疫, squid

Abstract: To study the hypolipemic and immunity effect of mucin glycoprotein from squid ( MGS ) ， the in habiting activity of pancreatic lipase was measured firstly in vitro. And then，hyperlipidemia model of mice was established to study the activity of reducing blood lipid level. The activity oi immunity was detected also in mice vivo. Results showed that MGS could inhibit the activity of pancreatic lipase in vitro. In the animal test，MGS could remarkably reduce the level of serum TC and LDL - C ，and improve the level of HDL - C ( P <0. 05 ) . However，MGS could reduce the level of TG indistinctively. Meanwhile，MGS could keep the weight from increasing on a certain extent. In addition，the difference of the carbon clearance index and phagocytic index between the control group and the sample group were no significant difference in statistics.